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Selected Publications

Granitzer S.,  Widhalm R., Atteneder S., Fernandez M. F., Mustieles V., Zeisler H., Hengstschläger M., Gundacker C.
"BDNF and KISS-1 Levels in Maternal Serum, Umbilical Cord, and Placenta: The Potential Role of Maternal Levels as Effect Biomarker"
Exposure and Health. 2023; 29:1–17 doi: 10.1007/s12403-023-00565-w 

Bajard, L., Adamovsky, O., Audouze, K., Baken, K., Barouki, R., Beltman, J. B., Beronius, A., Bonefeld-Jørgensen, E. C., Cano-Sancho, G., de Baat, M. L., Di Tillio, F., Fernández, M. F., FitzGerald, R. E., Gundacker, C., Hernández, A. F., Hilscherova, K., Karakitsios, S., Kuchovska, E., Long, M., .  . Blaha, L. 
"Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations."
Environmental Research. 2023 217, 114650. https://doi.org/https://doi.org/10.1016/j.envres.2022.114650

Forsthuber M, Widhalm R, Granitzer S, Kaiser AM, Moshammer H, Hengstschläger M, Dolznig H, Gundacker C
"Perfluorooctane sulfonic acid (PFOS) inhibits vessel formation in a human 3D co-culture angiogenesis model (NCFs/HUVECs)."
Environ Pollut. 2022; 293:118543. doi: 10.1016/j.envpol.2021.118543

Appel, M., Forsthuber, M., Ramos, R., Widhalm, R., Granitzer, S., Uhl, M., Hengstschläger, M., Stamm, T., & Gundacker, C.
"The transplacental transfer efficiency of per- and polyfluoroalkyl substances (PFAS): a first meta-analysis."

J Toxicol Environ Health B Crit Rev. 2022; https://doi.org/10.1080/10937404.2021.2009946 

Granitzer S, Widhalm R, Forsthuber M, Ellinger I, Desoye G, Hengstschläger M, Zeisler H, Salzer H, Gundacker C.
"Amino Acid Transporter LAT1 (SLC7A5) Mediates MeHg-Induced Oxidative Stress Defense in the Human Placental Cell Line HTR-8/SVneo."
Int J Mol Sci. 2021; doi: 10.3390/ijms22041707. PMID: 33567754; PMCID: PMC7915079.

Ventura, C., Gomes, B. C., Oberemm, A., Louro, H., Huuskonen, P., Mustieles, V., Fernández, M. F., Ndaw, S., Mengelers, M., Luijten, M., Gundacker, C., & Silva, M. J.
"Biomarkers of effect as determined in human biomonitoring studies on hexavalent chromium and cadmium in the period 2008-2020" 
Environ Res. 2021; doi:10.1016/j.envres.2021.110998 

Kaiser AM, Aro R, Kärrman A, Weiss S, Hartmann C, Uhl M, Forsthuber M, Gundacker C, Yeung LWY.
"Comparison of extraction methods for per- and polyfluoroalkyl substances (PFAS) in human serum and placenta samples-insights into extractable organic fluorine (EOF)."
Anal Bioanal Chem. 2021; doi: 10.1007/s00216-020-03041-5. PMID: 33215313; PMCID: PMC7809006. 

Kaiser AM, Forsthuber M, Aro R, Kärrman A, Gundacker C, Zeisler H, Foessleitner P, Salzer H, Hartmann C, Uhl M, Yeung LWY
"Extractable Organofluorine Analysis in Pooled Human Serum and Placental Tissue Samples from an Austrian Subpopulation-A Mass Balance Analysis Approach."
Environ Sci Technol. 2021; doi: 10.1021/acs.est.1c00883. 

Gundacker C, Graf-Rohrmeister K, Gencik M, Hengstschläger M, Holoman K, Rosa P, Kroismayr R, Offenthaler I, Plichta V, Reischer T, Teufl I, Raffesberg W, Scharf S, Köhler-Vallant B, Delissen Z, Weiß S, Uhl M.

„Gene Variants Determine Placental Transfer of Perfluoroalkyl Substances (PFAS), Mercury (Hg) and Lead (Pb), and Birth Outcome: Findings From the UmMuKi Bratislava-Vienna Study.“

Front Genet. 2021 doi: 10.3389/fgene.2021.664946. PMID: 34220941; PMCID: PMC8242356.

Gundacker C, Forsthuber M, Szigeti T, Kakucs R, Mustieles V, Fernandez MF, Bengtsen E, Vogel U, Hougaard KS, Saber AT.

„Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility.“

Int J Hyg Environ Health. 2021 doi: 10.1016/j.ijheh.2021.113855. PMID: 34655857.

Forsthuber M, Kaiser AM, Granitzer S, Hassl I, Hengstschläger M, Stangl H, Gundacker C.
"Albumin is the major carrier protein for PFOS, PFOA, PFHxS, PFNA and PFDA in human plasma." Environ Int. 2020; doi: 10.1016/j.envint.2019.105324. PMID: 32109724.

Widhalm R, Ellinger I, Granitzer S, Forsthuber M, Bajtela R, Gelles K, Hartig PY, Hengstschläger M, Zeisler H, Salzer H, Gundacker C.
"Human placental cell line HTR-8/SVneo accumulates cadmium by divalent metal transporters DMT1 and ZIP14."
Metallomics. 2020; doi: 10.1039/d0mt00199f. PMID: 33146651. 

Granitzer S, Ellinger I, Khan R, Gelles K, Widhalm R, Hengstschläger M, Zeisler H, Desoye G, Tupova L, Ceckova M, Salzer H, Gundacker C.
"In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta."
Arch Toxicol. 2020; doi: 10.1007/s00204-020-02900-5.  PMID: 32915249; PMCID: PMC7603445. 

Gundacker C, Ellinger I.
"The unique applicability of the human placenta to the Adverse Outcome Pathway (AOP) concept: the placenta provides fundamental insights into human organ functions at multiple levels of biological organization."
Reprod Toxicol. 2020; doi: 10.1016/j.reprotox.2020.07.014. PMID: 32768559.

Gundacker C, Kutalek R, Glaunach R, Deweis C, Hengstschläger M, Prinz A.
"Geophagy during pregnancy: Is there a health risk for infants?"
Environ Res. 2017; doi: 10.1016/j.envres.2017.03.028. PMID: 28342960. 

Gundacker C, Hengstschläger M.
"The role of the placenta in fetal exposure to heavy metals."
Wien Med Wochenschr. 2012; doi: 10.1007/s10354-012-0074-3. PMID: 22717874. 

Gundacker C, Fröhlich S, Graf-Rohrmeister K, Eibenberger B, Jessenig V, Gicic D, Prinz S, Wittmann KJ, Zeisler H, Vallant B, Pollak A, Husslein P.
"Perinatal lead and mercury exposure in Austria."
Sci Total Environ. 2010; doi: 10.1016/j.scitotenv.2010.07.079. PMID: 20825977

Gundacker C, Pietschnig B, Wittmann KJ, Lischka A, Salzer H, Hohenauer L, Schuster E.
"Lead and mercury in breast milk."
Pediatrics. 2002; doi: 10.1542/peds.110.5.873. PMID: 12415023.